The West Virginia. Cyclopedia
The Ohio Valley, in West Virginia, follows the Ohio River from the north near Chester, WV, (near its source at Pittsburgh, PA), southwest to near Huntington, WV, at its junction with the Big Sandy River.
Ohio Valley Communities:
Many towns along the river were trade centers in the late 1800s, though much of the valley along the river is wooded, or in pasture, and is prized for its scenic value. Farms of various size are located on ridge tops and along the river's many tributaries. Much of the valley, particularly in the north, is part of the U.S. Manufacturing Belt, or "Rust Belt," and intermittent stretches of the valley are industrialized. Three of the largest cities in West Virginia -- Wheeling, Huntington, and Parkersburg -- are located in the valley.
The term "Ohio Valley" in its broadest sense is sometimes used to describe the entire drainage of the river, in which case almost all West Virginia is contained in the valley. The valley is often described in terms of the West Virginia counties in which its valley-proper is contained, from the North: Hancock County, Brooke County, Ohio County, Marshall County, Wetzel County, Tyler County, Pleasants County, Wood County, Jackson County, Mason County, Cabell County, Wayne County.